[Correlation between manager's leadership style and the implementation process of "mother friendly hospital plan" in selected hospitals in west of country Iran [Kordestan, Hamedan and Kermanshah provinces] in 1391]

Regarding the worldwide efforts to implement and improve mother friendly services, and the rights of mothers for receiving quality care, there is a need for effective leadership and management of these hospital resources. Research in health sectors has shown that managers' leadership style is related to effectiveness, efficiency, productivity. The purpose of this study, was to examine the relationship between leadership style and implementation process of the "mother friendly Hospital Initiative" in selected hospitals in the West Country [province of Kurdistan, Hamedan and Kermanshah] in 1391. The study had a descriptive, correlational design. leadership style was measured by two questionnaires using a 5 point Likert scale, and a checklist for assessing the implementation of mother friendly services. The questionnaire were completed by managers and hospital personnel. The sample of the study consisted of 37 managers and 333 employees in selected hospitals in the provinces of Kurdistan, Hamedan and Kermanshah participated in this study. Initiatives process of the mother friendly hospital was evaluated by the monitoring list of mother friendly hospital in ministry of health. Validity of the questionnaire was assessed by content validity method and, the reability of the questionnaires was determined by internal consistency [r=0.798] for managers, [r=0.89] for staff, and the reability of the monitoring check list of mother friendly hospital was assured by inter-rater method [rS0/885]. Data were analyzed done by Chi-square, Fisher Exact Test, Pearson correlation and one way anova tests using the SPSS software [version 16]. The results showed that leadership style of managers' views are as follows: 67.6% Management consulting style, 24.3% benevolent- Autocratic style and the leadership style of 8.1% was Participative. While 61% from the employee's perspective, leadership styles used by managers, was benevolent-Autocratic, 21.3% consulting, 14.4% Autocratic - exploitation, 3.3% participative. It can be said that the results were Relatively satisfactory in about the process of implementing measures in mother friendly hospitals and There is significant relationship between the leadership style employed in the first third. Fifth, eighth and ninth proceedings in views of managers and employees from the perspective of the second, fourth and seventh steps, based on ANOVA. So th, the average ratio was higher in e authoritarian leadership style compared with and collaborative consulting style The findings of this study showed that autocratic leadership style was positively correlated to more accelerated implementation of mother friendly hospital practices

Development and implementation of health technology assessment: a policy study

To provide an overview of the development of health technology assessment [HTA] in Iran since 2007, and to facilitate further development of HTA and its integration into policy making. Data of this study were collected through key documents [e.g. literature, laws, and other official documentation] and analyzed by experts of opinion in form of qualitative methods. Health technology assessment entered to the political agenda in Iran only in 2007 with a strong impetus of an evidence-based medicine movement with the bellow objectives: Institutionalization of evidence-based decision making in Ministry of Health, Creating an localization for structural HTA in Health system of Iran, Setting up training courses in order to educate capable manpower to full up the capacity of the universities, Establishment of a new field in HTA subject in medical universities for MSc and PhD degree, International communication about HTA through national website and possible participation in international Congress. HTA has been established in the healthcare system of Iran but what is needed is a clear political will to push forward the objectives of HTA in Iran. Similar to other countries, advance the regulation on the adoption of new health technologies to improve not only technical or allocate efficiency, but also health equity

Common methods to treat addiction in treatment- rehabilitation centers in Tehran

This study was to determine common methods to treat addiction used by patients checked into Outpatient Treatment and Rehabilitation Clinics in Tehran. The study was conducted in Social Security affiliated outpatient clinics including three governmental and several private centers in 22 districts of Tehran. Demographic data, personal information, social characteristics and information regarding prevention, treatment, and follow-up records of 1,372 patients were obtained and analyzed. A majority of cases referring to the treatment centers were male [95.2%]. Patients were 14 to 75 yr [mean 35.48 +/- 10.57 yr]; 61.7% were married and lived in rented homes in the city; 938/1372 [68.4%] had at least one previous attempt failure when seeking re-treatment. A majority of them [77.8%] had a history of 1 to 4 quit attempts; a number 63.1% had an abstinence period of 1 week to 6 months. The majority of our understudy subjects had a history of previous attempts to treat their addiction with a maximum abstinence period of 6 months

[Incidence of post general anesthesia complications in recovery room]

General anesthesia and surgery cause several physiological disorders in different organs of the respective patients that may appear as several complications during recovery, which need to be identified and evaluated. Survey of the incidence of such complications at Post Anesthesia Care Unit [PACU] 1 and some of the effective risk factors in Rasht Razi Hospital. In this cross-sectional and descriptive study, 155 patients 10-75 years old, in ASA 1 and 2 classes were selected in the hospital. Cases included those who underwent general anesthesia with the same techniques for elective urology surgery and transferred to PACU, in 2010. Questionnaires consisted of two parts, part one included basic information and part two included: respiratory, cardiovascular, neural and digestive complications. Collected data were analyzed using chi-s quare, paired tests by SPSS 16 and P

direct medical costs of colorectal cancer in Iran; analyzing the patient's level data from a cancer specific hospital in Isfahan

The Immense cost of cancer treatment is one of the main challenges of health care systems all over the world including Iran. The aim of this study was to analyze the direct treatment costs of colorectal cancer patients in Isfahan, Iran. In this cross sectional study, the medical records of colorectal cancer [CRC] patients admitted to the Seyyed-al-Shohada Hospital "SSH" from 2005-2010 were reviewed. The profiles of 452 patients were examined. However based on inclusion, exclusion criteria a total number of 432 profiles were analyzed. All records including age, sex, treatment processes and treatment costs were extracted from the patients' profiles and analyzed using Kruskal-Wallis test. The results showed that 56.1% of CRC patients were male. The mean age of patients suffering from CRC was 56 +/- 13.4. More than Thirty-six percent of the patients were in stages 1-3 of CRC and more than half of them [64.4%] were in the 4[th] stage. The higher the stage of the cancer the higher the percentage of treatments used. 5-Fluorouracil and Leucovorin [5FU/LV] was the most common used chemical treatment protocol. The mean treatment cost for stage one was 10715 [ +/- 4927], for stage two 15920 [ +/- 3440], stage three 16452 [ +/- 2828] and for stage four was 16723 [ +/- 2555] US Dollars. The cost of drug treatment was the first cost driven between the medical services. CRC in Iranian population starts in younger age than people in western countries. This imposed considerable direct and indirect economic cost to the society. The direct medical cost of colorectal cancer in Iran is very higher than 38 million [dollar sign]. Screening programs could reduce the economic cost of CRC significantly

[Dietary intake in people with spinal cord injury based on sex, obesity and injury related variable in brain and spinal injury repair research center]

Despite an increased risk of obesity and CHD in people with spinal cord injury [SCI], there is little known about the dietary intake in this group, therefore the aim of this study was to examine nutrient intake and body mass index [BMI] in the spinal cord injury [SCI] population according to level of injury and related variables. In this cross-sectional study, 162 patients with spinal cord injury participated from Brain and Spinal Injury Repair research Center, Tehran, Iran. Dietary intakes were assessed by means of a semi quantitative food frequency questionnaire. The mean age of study population was 34.1 +/- 0.6 years. Total energy and carbohydrate intake were higher in men than women [P<0.001]. Incomplete injured consumed more MUFA [P=0.03]. The elderly were consumed less total calorie, saturated fat, MUFA, cholesterol [P<0.01] and PUFA [P<0.05]. Injured patients with longer times had lower total calorie, carbohydrate [P<0.01], total fat and MUFA intake [P<0.05]. Based on new classification 60.5% were at the risk of obesity or obese. Central obesity was seen in 33.1%of man and 48.4% of women. BMI of the paraplegia group was greater than that of the tetraplegia group [P=0.009]. Macronutrients balance is moved towards higher saturated fat intake and less complex carbohydrates and protein intake in SCI patient's. The elderly and patients who had lived with SCI longer time tended to maintain healthier diets

comparison in cosmetic results of cobalt 60 and photon 9 mega volt for the whole breast radiotherapy in breast cancer patients with breast conserving surgery

To compare the cosmetic results of whole breast radiotherapy between cobalt 60 and photon 9MegaVolt in patients underwent breast conserving surgery. The patients with breast saving surgery who were treated by whole breast radiotherapy with either cobalt 60 or photon 9MV between 2001-2006 in Sayed-al-Shohada hospital entered the study. The cosmetic results were evaluated by an expert radiation oncologist with definite criteria. Frothy patients in cobalt 60 group and 43 patients in photon group were compared, with median follow up of 40.5 months. The patients in photon group had less telangectasia and discoloration [p=0.018 and p=0.01, respectively]. The consistency of breast in photon group was better [p=0.019], but for fibrosis the difference was not statistically significant [p=0.055].Overall cosmetic results in photon group was much better rather than cobalt 60 group [p=0.005]. No recurrences were observed in both groups. Cosmetic results in group with photon 9MV were superior to cobalt group, but the effect of these two beam energy on disease free survival [DFS] and/or overall survival [OS] should be in more consideration

Sensitivity and specificity of colorectal cancer mass screening a systematic review of the literature

Colorectal cancer is the second cause of the cancer related mortalities in the world. Screening can effectively reduce the mortality and morbidity rate of this cancer. Sensitivity and specificity of screening methods play an important role in their efficacy. The aim of this study is to review sensitivity and specificity of selected colorectal cancer screening methods systematically. This study conducted a systematic review of sensitivity and specificity of five common colorectal cancer screening methods. The sites Pubmed, Cochrane library and the center for review and dissemination [CRD database] were searched systematically in Jan 2009. Key questions for this search were focused on the sensitivity and specificity of the 5 screening methods. In these databases 2713 articles were matched well with our subject. Of these 130 articles were selected with specified inclusion-exclusion criteria. The mean +/- standard deviation per patient sensitivities of colonoscopy, sigmoidoscopy, double contrast barium enema, CT colonography and fecal occult blood test for detecting colorectal cancer were respectively 94.7 +/- 4.6%, 82.0 +/- 9.3%, 82.3 +/- 8.7%, 95.7 +/- 5.9% and 45.7 +/- 26.5%. Specificities of these tests were respectively 99.8 +/- 0.2%, 83.9%, 92.4 +/- 14.7%, 98.5 +/- 1.3% and 87.6 +/- 11.4%. Based on available evidences, colonoscopy has the highest sensitivity and specificity among the selected screening methods and fecal occult blood test has the lowest sensitivity. Almost all of the tests except stool exams have acceptable sensitivity and specificity for detecting colorectal cancer

[Extra-intestinal symptoms and their relationship to psychological symptoms in patients with irritable bowel syndrome]

Irritable bowel syndrome [IBS] is one of the most common functional gastrointestinal disorders. A significant number of IBS patients have extra-intestinal symptoms [EIS], but the etiology of co-morbidity of IBS with these symptoms is unclear. The aim of this study was to evaluate the relationship of EIS with psychological symptoms in IBS patients. This multicenter, cross-sectional study was conducted on 18 to 65 year old IBS patients [Rome III criteria] referred to four gastroenterology outpatient clinics in the city of Isfahan from 2008-2009. Patients completed the IBS symptom severity scale, EIS severity scale, and anxiety and depression scale. Linear regression analysis was applied to evaluate the relationship of psychological symptoms with EIS, controlling for other variables. During the study period, 142 IBS patients [mean age=30.9 +/- .1 years, 81.7% female] were included. ESI score was significantly correlated to IBS severity score [r=0.534], anxiety [r=0.551] and depression scores [r=0.407]; P<0.001. With linear regression analysis, female gender [P=0.028], IBS severity [P<0.001], and severity of anxiety [P=0.001] were related to ESI scores. According to these results, psychological symptoms are associated with EIS in IBS patients, though prospective studies are needed to evaluate a causative association. Thus, gastroenterologists must pay attention to the association of psychological symptoms with EIS in the treatment of IBS patients and refer them for appropriate therapies

Learning critical thinking in virtual medical education: a qualitative study of faculty members' and students' experiences

Background and Purpose: Critical thinking is a high priority outcome of higher education. With the ever-increasing spread of virtual courses, enhancement in the critical thinking in distance learning has become the center of attention for the stakeholders

The present study was conducted to qualitatively examine the experiences of teachers and students in teaching and learning critical thinking in medical education

Methods and Materials: In this qualitative study, 7 E-teachers and 11 postgraduate E-students of medical education were interviewed using a semi-structured method. All interviews were tape-recorded, transcribed and then analyzed through constant comparison based on Strauss and Corbin's method

Results: Three themes were identified in this study; nature of critical thinking, critical thinking within the framework of medical education discipline; and the teaching-learning process of critical thinking in the virtual environment

Conclusion: The participants' experiences indicated that the learning-teaching of critical thinking in virtual education is affected by teaching strategies, the features of course management software, creation of a learner-centered environment and the role of critical thinking as one of the objectives of curriculum and evaluation

Assessment of patients skin dose undergoing coronary angiography and percutaneous transluminal coronary angioplasty [PTCA]

Practice of interventional cardiology procedures such as Coronary angiography [CA] and percutaneous transluminal coronary angioplasty [PTCA] has largely increased in recent years and is now changing to a matter of routine in many hospitals. The purpose of this study was to measure skin and organ doses in patients undergoing CA and PTCA and to find a probable relation with cardiologist's work experience. A group of 57 patients who were admitted to Nour and Chamran hospitals, Isfahan, Iran, either for CA [n=37] or PTCA [n=20] was checked for skin, eyes and thyroid gland radiation dose. Skin dose measurement was carried out with thermoluminescent dosimeters [TLD-100] placed at three different positions on the patients' bodies. Also the thyroid and eye doses were measured using the same procedure. Mean median, standard deviation and maximum doses for these results are presented. Maximum values found for skin in CA, PTCA, thyroid gland and eyes were 41.00, 73.90, 3.10 and 1.43 cGy, respectively. Average exposure time for CA and PTCA was 4.2 +/- 2.6 and 10.8 +/- 8.2 minutes, respectively. Radiation dose to the critical areas in each procedure in addition to its relation to the type of procedure was studied. Correlation between maximum skin dose and cardiologists' work experience was also investigated. 85% of the cases in CA and 78% of cases in PTCA received maximum skin dose of lower than 25cGy well below the threshold of 2 Gy suggestions for transient erythema

Educational programs' quality assessment based on graduates' comments

The specific goal of this study was quality assessment the educational programs of basic and clinical sciences of Tehran University of Medical Sciences [TUMS] according to the graduates' viewpoints. We obtained the list of all 1200 graduates of TUMS in 2007. Using a random generation table, 350 subjects were selected from the seven faculties of TUMS in proportion to the number of graduates from each faculty. The data collection device was a 15 item researcher-made questionnaire according to the existing problems in the educational system of the university. All the items of the questionnaire were constructed and standardized in terms of validity and reliability based on the latest reliable sources and textbooks on educational assessment [Likert indices]. Cronbach alpha was estimated to be 0.85. The most satisfaction from educational programs in basic sciences and clinical sciences was related to practical skills [4.36 +/- 1.22] versus satisfaction with education [4.76 +/- 1.66]. The quantity indices in basic sciences were 68.44% [3.42] which is in a fairly optimal range; for clinical sciences it was 77.2% [3.86], being also in an optimum range. TUMS must make an attempt to reach the optimal point in every educational aspect

effects of arsenic trioxide and zoledronic acid on malignant plasma cells derived from bone marrow cells of multiple myeloma patients

Multiple myeloma [MM] is a disease of plasma cells that has fatal consequences. New agents associated with molecular targets have prompted clinical investigators to design new treatment strategies initially for advanced MM and later for newly diagnosed MM, with encouraging preliminary results. We devised a project to assess the mechanisms of action of two drugs, Arsenic trioxide [ATO] and Zoledronic acid [Zometa] on Bone marrow mononuclear cells [BMMCs] derived from patients. Bone marrow samples were collected from 10 patients after receipt of formal consent. BMMCs were collected from samples. In two parallel sets of experiments, BMMCs were treated with 0.5, 2, 6 micro M ATO and 0.1, 10, 100 micro M Zometa, for 72 h. The following analyses were then performed on treated cells as compared to untreated cells [assumed as control]: cytotoxicity using Micro culture tetrazolium test [MTT assay]; matrix metalloproteinase-2 zymography; comparative gene expression analysis of IL-6, vascular endothelial growth factor [VEGF] and intercellular adhesion molecule-1 [ICAM-l]. MTT assay showed significant proliferation inhibition in ATO high dose treatment [6 uM]. However, no significant inhibitory effect of Zometa was seen. Zymography analyses showed significant decrease in gelatinolytic activity in treated cells. Analyses of gene expression using Real-Time RT-PCR methodology showed significant decrease in IL-6, ICAM-1, and VEGF genes as normalized against Hypoxanthine phosphoribosyltransferase normalizer and as compared with untreated cells. Both ATO and Zometa could significantly decrease MM cells critical phenotype and genotype. This finding could support the hypothesis that ATO or Zometa could inhibit growth and metastasis of malignant cells

satisfaction of medical practitioners from continuing medical education program of Tehran university of medical sciences

The concept of Continuing Medical Education in medical sciences has been rapidly gaining popularity during the last decades. The objective of this study was to assess the satisfaction of medical profession graduates participating in the programs of Continuing Medical Education [CME] in terms of their professional requirements. In a cross-sectional, descriptive analytical study, a reliable and valid retest questionnaire was used to determine the satisfaction from continuing medical education CME program. One hundred and three medical profession graduates who had participated in CME program in 2006 were enrolled. The satisfaction for anesthesiologists with the compatibility of CME programs with their professional requirements was 28.3%; for general practitioners and pediatricians with the capability of professors in presenting the program, 40%; and for gynecologists and obstetricians with the capability of 31.6%. We conclude from the results of this study that a high satisfaction was noticed among medical professionals that may be due to previous works of researchers who have assessed the needs precisely and standardized the modern teaching methods

[ effect of inclined bite plane and modified FRII treatment on dentoskeletal changes in CL II/I malocclusion]

The prevalence of Cl II malocclusion is high in the population. The functional appliances are used in the patient who has mandibular deficiency. The present study was aimed to compare thc dentoskeletal changcs of CLII/I Malocclusion who used inclined anterior bite plan and modified FRII. The material consisted of 30 patients, with Cl II/I malocclusion, ANB > 4° in late mixed dentifion. Half of the patients [9 girls and 6 boys] were treated by inclined anterior bite plane and reminder [8 girls and 7 boys] by modified FRII appliance. Lateral cephalogroms were obtained and traced before and after treatment and certain angular and linear variables were measured. The pretreatment and post-treatment measurements were compared using Mann-whitney U test and Wilcoxon Test to evaluate the significancy of the results. Significant changes mainly caused by mandibular growth, were observed after treatment by modified FRII and inclined anterior bite plane. This study indicated no statistical significant differences between two groups except Ar-B and AR-Pog. Considering the less bulky anterior inclined bile plane and its easier construction we can use this appliance instead of modified FRIT

Prevalence of celiac disease in patients with irritable bowel syndrome

Celiac disease [CD] may be misdiagnosed as Irritable Bowel Syndrome [IBS] resulting in long delays in diagnosing CD. There are contradictory reports on the association of CD with IBS. Appropriateness of screening all patients with IBS for CD and how to screen them are still under question. In a cross-sectional study, 328 IBS patients [Rome II] referred to the Poursina Hakim Gastroenterology Clinic were investigated for CD. Total serum anti-tissue transglutaminase IgA [anti-tTG IgA] concentration was measured in all patients. In IgA deficient cases, antigliadin antibody [AGA] IgG concentration was also measured. Moreover, in patients who underwent upper endoscopy [as their necessary workup] duodenal biopsies were taken. Fifty-eight patients were excluded. The remaining patients were 166 [61.5%] women and 104 [38.5%] men with the mean age of 35.3 years [SD = 11.8]. No one had positive serological test of IgA anti tTG antibody. Five patients were IgA deficient; none of them had positive IgG AGA. Duodenal biopsies were taken in 60 patients and pathologic evaluation showed 53Marsh 0, three Marsh I, three Marsh II, and one Marsh IIIa. Only the patient with Marsh IIIa adhered to gluten-free diet [GFD] which led to decrease in severity of symptoms. In patients who did not adhere to GFD, no one had positive serological test after 12 months of follow-up. Prevalence of CD in patients with IBS referred to outpatient gastroenterology clinic might be significant but serum anti-tTG IgA antibody is not helpful in detecting CD in these patients. Further studies are needed to clarify this issue

[Childhood tuberculosis in Iran: trends over the 1992-2005 period]

Children are highly vulnerable to TB and childhood tuberculosis is a sign of TB transmission in community. This study aimed to determine the epidemiologic trend of this disease in Iranian children. A Trend Study was conducted to evaluate all Iranian patients aged below 14 who had been diagnosed with pulmonary or extrapulmonary TB from 1992 to 2005. Statistical relationships were tested using chi square tests [CHI[2]] and the software package SPSS [version 11.5]. Out of the 6168 cases studied, 2528 [40.1%] were boys. Patients were assigned to three groups based on disease type: there were 1812 [29.4%] sputum- positive, 1920 [31.1%] sputum-negative, and 2449 [39.7%] extrapulmonary cases. The incidence of sputum-positive TB declined from 0.8 per 100000 in 1992 to 0.2 per 100000 in 2005. A similar declining trend was observed for the overall TB incidence and in the incidence of sputum-negative and extrapulmonary cases. There was significant difference in TB incidence between girls and boys in the 10-14 year age group [P<0.001], but no sex difference was observed in 0-4y and 5-9y age groups. The incidence of sputum-positive TB decreased by 75 percent over the study period. This could be partly due to improvements in health status, better disease knowledge and the effects of Iran's National TB Control Program. In children aged below 10 years, there was no significant difference in the incidence of tuberculosis between girls and boys. At puberty, the incidence of all types of TB was higher in girls. Based on these findings, further studies are needed to elucidate the gender distribution of childhood tuberculosis in Iran

Satisfaction evaluation of blood donors of Iranian Blood Transfusion Organization in 2003

Satisfaction of blood donors plays a critical role in providing safe and adequate blood supply for patients. This study aimed to evaluate the level of satisfaction of blood donors in Iranian Blood Transfusion Organization [IBTO]. This was a cross-sectional study with the involvement of 2508 blood donors selected in proportion to the average distribution of blood donors in different provinces of Iran. The random sampling method was used. Questionnaires were directly handed over to blood donors. There was a positive relationship between behavior of physicians or other care staff with satisfaction level of blood donors. Physical conditions of donation sites play an important role in satisfaction level of blood donors. There was a negative correlation between education level and satisfaction of blood donors; the higher the education level, the less the rate of satisfaction. There was not any significant difference in satisfaction of blood donors in terms of sex. Satisfaction rate of blood donors was higher among those referring to blood drives than those to blood centers. Satisfaction rate among repeat blood donors was more than twice that among first-time blood donors [PVO.04]. The highest satisfaction value is attributed to the behavior of the personnel involved in phlebotomy and physicians. The lowest satisfaction value pertained to accessibility of blood donor centers. Overall satisfaction rate was more than 50% showing a figure, higher than our previous estimation

[Incidence rate of pulmonary tuberculosis among different ethnicities in Golestan province from 1999 to 2003]

Over the last few years, the province of Golestan has ranked second among all Iranian provinces in terms of TB prevalence after Sistan and Balochestan. The present study was done with the aim of evaluating the incidence of TB among different ethnic groups residing in Golestan. In a descriptive study, all TB patients including sputum smear-positive and negative, extra-pulmonary, and milliary cases were evaluated from 1999 to 2003. The incidence of all types of TB was compared among different ethnicities in the province. Forty-seven percent of the 2773 cases registered for Golestan Province in the Communicable Disease Control Center from1999 to 2003 were male. As regards the type of disease, 62.7% of the cases were sputum smear-positive, 16.4% were smear-negative, 20.7% had extra-pulmonary disease, and 0.1% was milliary TB cases. The incidence rate of all types of TB was 36 per 100000 populations and the rate did not show any significant changes over the study period. As for the ethnic distribution of the cases, more than 50% of all TB cases were observed among Sistanis and Baluches, who together account for only 20% of all Golestan residents. The incidence in Sistanis was ten times that in Turks and Kurds, six times that in Persians, 4 times the rate in Torkamans, and 2.5 times that in Afghans living in the same region. The incidence rate of tuberculosis was significantly different among various ethnicities of Golestan province, being highest in Sistanis

[Investigation of validity and reliability of Persian version of the "St. George Respiratory Questionaire"]

Health related quality of life [HRQL] questionnaires allow clinicians to measure daily the impact of disease on a patients daily life and is valuable in clinical trial designed to assess benefits and costs of management. We describe the adaptation into Persian version of the St.George Respiratory Questionnaires [SGRQ]; a recognized valid self administered questionnaire for chronic obstructive pulomnary diseases. In order to adapt the face validity, the forward and back- translation method was used. Then this questionnaire was edited by researchers and a single pulmonologist as an internist. The content of tests evaluated for feasibility and comprehension by 15 educated COPD patients. In following, the professional committee of researcher assessed the content validity. At last, 55 COPD patients with wide range of disease severity fulfilled the Persian version of the SGRQ. Internal consistency were measured by Cronbach's alpha coefficient test. The test coefficiency for reliability was 0.74 in part I of questionnaire; "symptoms". Factor analysis indicated that if latest question of part 1 was eliminated ["If you wheeze, is it become worse in the morning?"] Cronbach's alpha would be elevated to 0.78. Cronbach's alpha was 0.95 in Part II [Activity and impact] and for overall scale, the result was found to be 0.93. Data from this study revealed that Persian version of SGRQ, as a research tool, is of good validity and sufficient reliablity. The present study suggest the feasibility of adapting a specific instrument of health related quality of life in patients with respiratory disease to be used in different settings from where the instrument has been originally developed